References

 

Recommended Reading:

For all aspects of the immune system, the following text is recommended:

 

Janeway, C.A., Travers, P., Walport, M. and Shlomchik, M. (2004). Immunobiology, the Immune System in Health and Disease 6th Edition Churchill Livingstone, ISBN: 0443073104.

 

Janeway, Travers, Walport and Shlomchik on Amazon.co.uk


 

References:

Specific references for each section:

 

1.      Introduction

1. Burnet, F. M. (1957) A modification of Jerne’s theory of antibody production using the concept of clonal selection. Australian Journal of Science 20, 67-69

Burnet, F. M. (1959) The Clonal Selection Theory of Acquired Immunity. Cambridge University Press, Cambridge.

Frosdyke, D. R. (1995) The origins of Clonal Selection Theory of Immunity. A Case Study for the Evaluation of science. FASEB Journal 9: 164-6

 

2.      The Enemy

2. http://www-micro.msb.le.ac.uk/224/Malaria.html

Madiagan, M.T., Martinko, J.M. and Parker, J. (1997) Brock Biology of Microorganisms 8th Edition Prentice Hall International, London. ISBN: 0-13-571225-4

Cann, A.J. (1997) Principals of Molecular Virology 2nd  Edition Academic Press, London. ISBN: 0-12-158532-8

 

3.      The Home Team

Janeway, C.A., Travers, P., Walport, M. and Shlomchik, M. (2004). Immunobiology, the Immune System in Health and Disease 5th Edition Churchill Livingstone, ISBN: 0-4430-7098-9.

http://www-micro.msb.le.ac.uk/mbchb/2a.html

 

4.      Innate Immunity

Janeway, C.A., Travers, P., Walport, M. and Shlomchik, M. (2004). Immunobiology, the Immune System in Health and Disease 5th Edition Churchill Livingstone, ISBN: 0-4430-7098-9.

 

5.      Fighting Bacterial Infections:

a)      Phagocytes

Andrew, P.W. (1998-9) Undergraduate Lecture series, University of Leicester

Lewis, C.E. and McGee, J. O’D. (1992) The Macrophage: The Natural Immune System. Oxford University Press. ISBN 0199632340

Abramson, J.S. and Wheeler, J.G. (1993) The Neutrophil: Natural Immune System. Oxford University Press. ISBN: 0199633738

 

b)      Antibodies and B Lymphocytes

Janeway, C.A., Travers, P., Walport, M. and Shlomchik, M. (2004). Immunobiology, the Immune System in Health and Disease 5th Edition Churchill Livingstone, ISBN: 0-4430-7098-9.

 

Hewitt, C. (1999) Undergraduate lecture series. University of Leicester.

Goodenow, C.C. et al (1995) Self tolerance checkpoints in B cell development. Advanced Immunology 59: 279-368

Winkler, T. and Rolnik, A.G. (1994) Roles of the Ig H-chain and L-chain and of surrogate H-chain and L-chain in the development of cells of the B-lymphocyte lineage. Annual Review of Immunology 12: 209-25

 

c)      Complement

Andrew, P.W. (1998-9) Undergraduate lecture series, University of Leicester

Frank, M.M. and Fries L.F. (1991) The role of complement in inflammation and phagocytosis. Immunology Today 12: 322-6

Tomlinson, S. (1993) Complement defense mechanisms. Current Opinions in Immunology 5: 83-9

 

6.      Fighting Viral Infections:

a)      The Major Histocompatibility Complex

Morrison, L.A., Lukacher, A.E., Braciale, V.L., Fan, D.P. and Braciale, T.J. (1986) Differences in antigen presentation to MHC class I- and MHC Class II-restricted influenza virus-specific cytolytic T-lymphocyte clones. Journal of Experimental Medicine. 163: 903

Klein, J. Satta, Y. O’Huigin, C. (1993) The molecular descent of the major histocompatibility complex. Annual Review of Immunology 11: 269-95

 

b)      Cytotoxic T-cells

Nossal, F.J.V. (1994) Negative selection of lymphocytes. Cell 76: 229-39

Von Boehmenr, H. (1994) Positive selection of lymphocytes. Cell 76: 219-38

Henkart, P.A. (1994) Lymphocyte-mediated cytotoxicology: two pathways and multiple effector molecules. Immunity 1: 343-6

 

c)      Natural Killer Cells

Vales-Gomez, M., Reyburn, H. and Strp,omher, J. (2000) Molecular analysis of the interactions between human NK receptors and their HLA ligands. Human Immunology 61: 28-38

Cann, A.J. (1997) Principals of Molecular Virology 2nd  Edition Academic Press, London. ISBN: 0-12-158532-8

 

 

 

7.      T Helper Cells and HIV

1. UNAIDS (2004), 2004 report on the global HIV/AIDS epidemic 4th global report. ISBN 92 9173 355 5 http://www.unaids.org/bangkok2004/GAR2004_html/GAR2004_00_en.htm

 

Cann, A.J. (1997) Principals of Molecular Virology 2nd  Edition Academic Press, London. ISBN: 0-12-158532-8

Mosmann, T.R. et al. (1989) Th1 and Th2 cells: different patterns of lymphokine secretion lead to different functional properties. Annual Review of Immunology. 7: 145-73

 

 

8.      Leukaemia and Lymphoma

Janeway, C.A., Travers, P., Walport, M. and Shlomchik, M. (2004). Immunobiology, the Immune System in Health and Disease 5th Edition Churchill Livingstone, ISBN: 0-4430-7098-9.

 

 

Monoclonal Antibody Technology

            Kohler, G. and Milstein, C. (1975). Continuous cultures of fused cells secreting antibody of predefined specificity Nature 256: 495-7

 

Vaccination

Cann, A.J. (1997) Principals of Molecular Virology 2nd  Edition Academic Press, London. ISBN: 0-12-158532-8

                http://www.immunisation.nhs.uk

                http://www.jennermuseum.com

               

Rhesus Disease

http://www.rcog.org.uk/press_releases.asp?PageID=944&PressReleaseID=33